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HRID1434850

反应详情

EQUATION

反应方程式

HRID 1434850 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CC(C)N=C[C@@H](C)COc1cc(S(C)(=O)=O)ccc1C(=O)Nc1cccnc1C(=O)Nc1ccc(Cl)cn1
HCID68982627

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H](CN)COc1cc(S(C)(=O)=O)ccc1C(=O)Nc1cccnc1C(=O)Nc1ccc(Cl)cn1.Cl
HCID68983189

未命名化合物

收率 69%

PROCEDURE

实验过程

N-(5-Chloropyridin-2-yl)-3-[2-[(2R)-2-methyl-3-(2-propylimino)propoxy]-4-methylsulfonylbenzoylamino]-pyridine-2-carboxamide was treated with 1 N HCl and purified by HPLC (Vydac C18, 5-70% 0.1% TFA/CH3CN in 0.1% TFA/H2O; Rt: 27.6 m) to give the title compound as a solid (205 mg, 69%).

WORKUP

后处理

  1. custompurified by HPLC (Vydac C18, 5-70% 0.1% TFA/CH3CN in 0.1% TFA/H2O; Rt: 27.6 m)