Benzo(B)Thiophene-2-Boronic Acid → HCID 57936160, compound

HRID 1434964Notes

Reaction equation

HRID 1434964 reaction equation
Cl[C:2]1[N:7]=[C:6](Cl)[CH:5]=[CH:4][N:3]=1.[S:9]1[C:13](B(O)O)=[CH:12][C:11]2[CH:17]=[CH:18][CH:19]=[CH:20][C:10]1=2.[CH2:21]([O:23][C:24]([N:26]1[CH2:31][CH2:30][CH:29]([NH2:32])[CH2:28][CH2:27]1)=[O:25])[CH3:22]>>[CH2:21]([O:23][C:24]([N:26]1[CH2:27][CH2:28][CH:29]([NH:32][C:2]2[N:7]=[C:6]([C:13]3[S:9][C:10]4[CH:20]=[CH:19][CH:18]=[CH:17][C:11]=4[CH:12]=3)[CH:5]=[CH:4][N:3]=2)[CH2:30][CH2:31]1)=[O:25])[CH3:22]

Participants

4

Reactant 3

HCID 2359Benzo(B)Thiophene-2-Boronic AcidHCID 775312,4-DichloropyrimidineHCID 100867Ethyl 4-amino-1-piperidinecarboxylate

Product 1

HCID 57936160HCID 57936160, compound

Procedure

The title compound was prepared analogous to Method A, starting from 2,4-dichloro-pyrimidine, benzo[b]thiophen-2-boronic acid and ethyl-4-amino-1-piperidinecarboxylate.

Sources & evidence

ORD record
ord-7a209bf490814adebb05bdae9d333e87
Source dataset
uspto-grants-2009_11
Patent number
US07615562B2

Reaction notes

Loading…