Benzo(B)Thiophene-2-Boronic Acid → HCID 57936256, compound

HRID 1434967Notes

Reaction equation

HRID 1434967 reaction equation
Cl[C:2]1[N:7]=[C:6](Cl)[CH:5]=[CH:4][N:3]=1.[S:9]1[C:13](B(O)O)=[CH:12][C:11]2[CH:17]=[CH:18][CH:19]=[CH:20][C:10]1=2.[NH2:21][CH:22]1[CH2:27][CH2:26][N:25]([CH2:28][C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH2:24][CH2:23]1>>[S:9]1[C:13]([C:6]2[CH:5]=[CH:4][N:3]=[C:2]([NH:21][CH:22]3[CH2:27][CH2:26][N:25]([CH2:28][C:29]4[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=4)[CH2:24][CH2:23]3)[N:7]=2)=[CH:12][C:11]2[CH:17]=[CH:18][CH:19]=[CH:20][C:10]1=2

Participants

4

Reactant 3

HCID 2359Benzo(B)Thiophene-2-Boronic AcidHCID 775312,4-DichloropyrimidineHCID 4158521-Benzyl-4-piperidylamine

Product 1

HCID 57936256HCID 57936256, compound

Procedure

The title compound was prepared analogous to Method A, starting from 2,4-dichloro-pyrimidine, benzo[b]thiophen-2-boronic acid and 4-amino-1-benzyl-piperidine.

Sources & evidence

ORD record
ord-0e265d18ce2c4574900e973cd552c7ba
Source dataset
uspto-grants-2009_11
Patent number
US07615562B2

Reaction notes

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