Benzo(B)Thiophene-2-Boronic Acid → HCID 57936202, compound

HRID 1434977Notes

Reaction equation

HRID 1434977 reaction equation
Cl[C:2]1[N:7]=[C:6](Cl)[CH:5]=[CH:4][N:3]=1.[S:9]1[C:13](B(O)O)=[CH:12][C:11]2[CH:17]=[CH:18][CH:19]=[CH:20][C:10]1=2.[CH3:21][C:22]1([CH3:30])[CH2:27][CH:26]([NH2:28])[CH2:25][CH:24]([CH3:29])[NH:23]1>>[S:9]1[C:13]([C:6]2[CH:5]=[CH:4][N:3]=[C:2]([NH:28][CH:26]3[CH2:25][CH:24]([CH3:29])[NH:23][C:22]([CH3:30])([CH3:21])[CH2:27]3)[N:7]=2)=[CH:12][C:11]2[CH:17]=[CH:18][CH:19]=[CH:20][C:10]1=2

Participants

4

Reactant 3

HCID 2359Benzo(B)Thiophene-2-Boronic AcidHCID 775312,4-DichloropyrimidineHCID 55281318HCID 55281318, compound

Product 1

HCID 57936202HCID 57936202, compound

Procedure

The title compound was prepared analogous to Method A, starting from 2,4-dichloro-pyrimidine, benzo[b]thiophen-2-boronic acid and 2,2,6-trimethyl-piperidin-4-ylamine.

Sources & evidence

ORD record
ord-09a4e7ca309e4d7e8515cf751a4467d4
Source dataset
uspto-grants-2009_11
Patent number
US07615562B2

Reaction notes

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