反应详情

温度

90 °C

To a 2 L two-necked round bottom flask equipped with water condenser, calcium chloride guard tube and mechanical stirrer, 70 g of 2,4-pentanedione, 650 g of 1-bromooctadecane, 8 g of 18-crown-6, anhydrous potassium carbonate 140 g and 600 ml of absolute ethanol were added with stirring. The mixture was refluxed at 90° C. with continuous stirring for 30 hrs; after refluxing at the said temperature, the mixture cooled to ambient temperature (25° C.), 600 ml of water was added to it and the 2-heneicosanone was extracted with dichloromethane from the mixture. On distillation of dichloromethane, 2-heneicosanone was obtained.

1. customTo a 2 L two-necked round bottom flask equipped with water condenser, calcium chloride guard tube and mechanical stirrer
2. stirringwith continuous stirring for 30 hrs
3. temperatureafter refluxing at the said temperature
4. additionwas added to it
5. extractionthe 2-heneicosanone was extracted with dichloromethane from the mixture
6. distillationOn distillation of dichloromethane