Dichloromethane → 1-(2-(4-(4-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamido)-2-fluorophenoxy)quinolin-7-yloxy)ethyl)cyclopropyl 2-(tert-butoxy-carbonylamino)acetate
Reaction equation
[C:43](=[O:44])([O:45][C:46]([CH3:47])([CH3:48])[CH3:49])[NH:50][CH2:51][C:52](=[O:53])[OH:54].[CH3:70][N:71]([c:72]1[cH:73][cH:74][n:75][cH:76][cH:77]1)[CH3:78].[CH:55]1([N:56]=[C:57]=[N:58][CH:59]2[CH2:60][CH2:61][CH2:62][CH2:63][CH2:64]2)[CH2:65][CH2:66][CH2:67][CH2:68][CH2:69]1.[Cl:79][CH2:80][Cl:81].[F:1][c:2]1[cH:3][c:4]([NH:26][C:27](=[O:28])[c:29]2[c:30](=[O:42])[n:31](-[c:36]3[cH:37][cH:38][cH:39][cH:40][cH:41]3)[n:32]([CH3:35])[c:33]2[CH3:34])[cH:5][cH:6][c:7]1[O:8][c:9]1[cH:10][cH:11][n:12][c:13]2[cH:14][c:15]([O:19][CH2:20][CH2:21][C:22]3([OH:25])[CH2:23][CH2:24]3)[cH:16][cH:17][c:18]12>>[F:1][c:2]1[cH:3][c:4]([NH:26][C:27](=[O:28])[c:29]2[c:30](=[O:42])[n:31](-[c:36]3[cH:37][cH:38][cH:39][cH:40][cH:41]3)[n:32]([CH3:35])[c:33]2[CH3:34])[cH:5][cH:6][c:7]1[O:8][c:9]1[cH:10][cH:11][n:12][c:13]2[cH:14][c:15]([O:19][CH2:20][CH2:21][C:22]3([O:25][C:52]([CH2:51][NH:50][C:43](=[O:44])[O:45][C:46]([CH3:47])([CH3:48])[CH3:49])=[O:53])[CH2:23][CH2:24]3)[cH:16][cH:17][c:18]12Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-847372e0daa04ddf8452729163b18868
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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