Methanol → Acyclovirvalericester

HRID 143663Notes

Reaction equation

HRID 143663 reaction equation
[C:22]([CH2:23][CH2:24][CH2:25][CH3:26])(=[O:27])[Cl:28].[CH3:17][N:18]([CH3:19])[CH:20]=[O:21].[CH3:29][N:30]([CH3:31])[c:32]1[cH:33][cH:34][n:35][cH:36][cH:37]1.[CH3:39][OH:40].[NH2:1][c:2]1[n:3][c:4]2[n:5]([CH2:6][O:7][CH2:8][CH2:9][OH:10])[cH:11][n:12][c:13]2[c:14](=[O:15])[nH:16]1.[OH2:38]>>[NH2:1][c:2]1[n:3][c:4]2[n:5]([CH2:6][O:7][CH2:8][CH2:9][O:10][C:22]([CH2:23][CH2:24][CH2:25][CH3:26])=[O:27])[cH:11][n:12][c:13]2[c:14](=[O:15])[nH:16]1

Participants

7

Reactant 6

HCID 887MethanolHCID 962WaterHCID 6228DimethylformamideHCID 142844-(Dimethylamino)pyridineHCID 61186Valeryl chlorideHCID 135398513Acyclovir

Product 1

HCID 135524524Acyclovirvalericester

Sources & evidence

ORD record
ord-fb4ae2f5e7e241be9b654614b3b8f7eb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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