Dimethylformamide → 3-amino-N-methyl-6-[4-(tetrahydro-2H-pyran-2-yloxy)phenyl]pyrazine-2-carboxamide
Reaction equation
[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[Cl:29][CH2:30][Cl:31].[NH2:1][c:2]1[c:3]([C:9](=[O:10])[NH:11][CH3:12])[n:4][c:5]([Br:8])[cH:6][n:7]1.[O:13]1[CH:14]([O:19][c:20]2[cH:21][cH:22][c:23]([B:26]([OH:27])[OH:28])[cH:24][cH:25]2)[CH2:15][CH2:16][CH2:17][CH2:18]1.[O:39]=[CH:40][N:41]([CH3:42])[CH3:43]>>[NH2:1][c:2]1[c:3]([C:9](=[O:10])[NH:11][CH3:12])[n:4][c:5](-[c:23]2[cH:22][cH:21][c:20]([O:19][CH:14]3[O:13][CH2:18][CH2:17][CH2:16][CH2:15]3)[cH:25][cH:24]2)[cH:6][n:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-0cafc7dca49f461bbe633f0d6bf5498d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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