反应详情

A solution of (b) (180 mg, 0.8 mmol) in DMF (5 ml) was treated with potassium carbonate (140 mg) and methyl iodide (0.062 ml) and stirred for 3 days then evaporated. The residue was partitioned between dilute aqueous sodium chloride solution and dichloromethane, re-extracting with dichloromethane twice more. The combined organic extracts were dried and evaporated affording a yellow solid (180 mg, 94%).

1. customthen evaporated
2. customThe residue was partitioned between dilute aqueous sodium chloride solution and dichloromethane
3. extractionre-extracting with dichloromethane twice more
4. customThe combined organic extracts were dried
5. customevaporated