反应详情

A solution of (c) (2.0 g, 6.2 mmol) in dichloromethane/methanol/acetonitrile (40 ml/4 ml/40 ml) was treated with triethylamine (1.1 ml, 8 mmol) then a solution of (trimethylsilyl)diazomethane in hexane (2M; 4 ml, 8 mmol). The mixture was stirred overnight then evaporated. The residue was chromatographed on silica eluting with dichloromethane affording an oil (1.0 g, 48%).

1. customthen evaporated
2. customThe residue was chromatographed on silica eluting with dichloromethane affording an oil (1.0 g, 48%)