反应详情

The title compound was synthesized in analogy to example 9, intermediate a), from (1-isopropyl-piperidin-4-yloxy)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid hydrochloride (example 13, intermediate b)), O-(benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate, morpholine and N,N-diisopropylethylamine (7 eq.) in DMF to give the desired product as a yellow solid (70%).