Acetate → (RS)-ethoxy-(2-oxo-3-phenylamino-2H-pyridin-1-yl)-acetic acid ethyl ester

HRID 143809Notes

Reaction equation

HRID 143809 reaction equation
[CH2:10]([CH3:11])[O:12][C:13]([CH:14]([O:15][CH2:16][CH3:17])[n:18]1[c:19](=[O:25])[c:20]([NH2:24])[cH:21][cH:22][cH:23]1)=[O:26].[CH3:27][C:28](=[O:29])[O-:30].[CH3:31][C:32]1([CH3:41])[N:33]([O:34])[C:35]([CH3:36])([CH3:37])[CH2:38][CH2:39][CH2:40]1.[CH3:45][CH2:46][N:47]([CH2:48][CH3:49])[CH2:50][CH3:51].[Cl:42][CH2:43][Cl:44].[OH:1][B:2]([OH:3])[c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1>>[c:4]1([NH:24][c:20]2[c:19](=[O:25])[n:18]([CH:14]([C:13]([O:12][CH2:10][CH3:11])=[O:26])[O:15][CH2:16][CH3:17])[cH:23][cH:22][cH:21]2)[cH:5][cH:6][cH:7][cH:8][cH:9]1

Participants

7

Reactant 6

HCID 175AcetateHCID 6344DichloromethaneHCID 8471TriethylamineHCID 66827Phenylboronic AcidHCID 5499762,2,6,6-Tetramethylpiperidin-1-olHCID 69641593(RS)-(3-amino-2-oxo-2H-pyridin-1-yl)-ethoxy-acetic acid ethyl ester

Product 1

HCID 69641585(RS)-ethoxy-(2-oxo-3-phenylamino-2H-pyridin-1-yl)-acetic acid ethyl ester

Sources & evidence

ORD record
ord-b0fa69d7a58041809276f9ab32943fe3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…