Hydrochloric Acid → HCID 68436532, compound

HRID 1438112Notes

Reaction equation

HRID 1438112 reaction equation
[CH:1]([S:4]([C:7]1[CH:12]=[CH:11][C:10]([N+:13]([O-])=O)=[CH:9][C:8]=1[C:16]1[N:17](C(OC(C)(C)C)=O)[CH:18]=[CH:19][CH:20]=1)(=[O:6])=[O:5])([CH3:3])[CH3:2].[ClH:28]>C(O)C.[Pt]=O>[ClH:28].[CH:1]([S:4]([C:7]1[CH:12]=[CH:11][C:10]([NH2:13])=[CH:9][C:8]=1[CH:16]1[CH2:20][CH2:19][CH2:18][NH:17]1)(=[O:6])=[O:5])([CH3:3])[CH3:2]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 57942715HCID 57942715, compound

Product 1

HCID 68436532HCID 68436532, compound

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 702EthanolSolvent

Procedure

To platinum oxide (0.16 g) was added 19C (0.4 g, 1.0 mmol) in ethanol (20 mL) and hydrogen chloride (0.15 mL) under nitrogen. The reaction was placed under hydrogen (30 psi) and stirred at rt for 1.5 h. The catalyst was filtered over celite and washed with ethanol and methanol. The filtrate and washings were combined and the solvent was evaporated to give 0.35 g of yellow solid 19D.

Workup

  1. filtrationThe catalyst was filtered over celite
  2. washwashed with ethanol and methanol
  3. customthe solvent was evaporated

Sources & evidence

ORD record
ord-f5cc9f2206a14fe4ad514db08f6499bd
Source dataset
uspto-grants-2009_11
Patent number
US07622585B2

Reaction notes

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