Hydrochloric Acid → HCID 68439959, compound

HRID 1438122Notes

Reaction equation

HRID 1438122 reaction equation
[CH:1]([S:4]([C:7]1[CH:12]=[CH:11][C:10]([N+:13]([O-:15])=[O:14])=[CH:9][C:8]=1[CH:16]1[CH:20]([C:21]([O:23][CH3:24])=[O:22])[CH2:19][CH2:18][N:17]1C(OC(C)(C)C)=O)(=[O:6])=[O:5])([CH3:3])[CH3:2].[ClH:32]>>[ClH:32].[CH:1]([S:4]([C:7]1[CH:12]=[CH:11][C:10]([N+:13]([O-:15])=[O:14])=[CH:9][C:8]=1[CH:16]1[CH:20]([C:21]([O:23][CH3:24])=[O:22])[CH2:19][CH2:18][NH:17]1)(=[O:5])=[O:6])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 579428471-tert-Butyl 3-methyl 2-(2-(isopropylsulfonyl)-5-nitrophenyl)pyrrolidine-1,3-dicarboxylate

Product 1

HCID 68439959HCID 68439959, compound

Procedure

To 20E (100 mg, 0.20 mmol) was added hydrogen chloride (1 mL, 4M solution in dioxane). After stirring for 2 h at rt, the reaction was triturated with ether and filtered to give 24A (90 mg) as a white solid.

Workup

  1. customthe reaction was triturated with ether
  2. filtrationfiltered

Sources & evidence

ORD record
ord-16f88b437042474a9ca8042b32a899b9
Source dataset
uspto-grants-2009_11
Patent number
US07622585B2

Reaction notes

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