Ammonia → HCID 3046207, compound

HRID 1439013Notes

Reaction equation

HRID 1439013 reaction equation
[NH2-:1].[Na+].N.[Na].[CH2:5]([C:8]([CH2:12][CH2:13][CH3:14])(Cl)[C:9]#[CH:10])[CH2:6][CH3:7]>C(OCC)C>[CH2:5]([C:8]([NH2:1])([CH2:12][CH2:13][CH3:14])[C:9]#[CH:10])[CH2:6][CH3:7]

Participants

6

Reactant 4

HCID 222Ammonia2×HCID 24533Sodium amideHCID 5360545SodiumHCID 123839014-Chloro-4-ethynylheptane

Product 1

HCID 3046207HCID 3046207, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

To a suspension of sodium amide in liquid ammonia, prepared from 6.9 g of sodium and 250 ml of liquid ammonia, were added 17 g of 1,1-di-n-propyl-1-chloro-2-propyne in 50 ml of anhydrous ethyl ether. The operation of adding the chlorinated derivative lasted one hour. Stirring of the mixture was maintained for 2 hours and then 300 ml of anhydrous ethyl ether were added.

Workup

  1. additionThe operation of adding the chlorinated derivative
  2. temperaturewas maintained for 2 hours

Sources & evidence

ORD record
ord-ac5ba1381e5741808c66b4cc76ef940a
Source dataset
uspto-grants-1977_11
Patent number
US04057644

Reaction notes

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