反应详情

1-(2-Chloroethyl)-4-phenylpiperazine dihydrochloride (3.3 g) was converted to the base and added to 1.2 g 5-Benzyloxyanthranilamide in 125 ml propanol. The solution was refluxed 3 hours, cooled, filtered, and the filtrate concentrated to dryness. The residue was chromatographed on alumina to give 0.63 g product.

1. temperatureThe solution was refluxed 3 hours
2. temperaturecooled
3. filtrationfiltered
4. concentrationthe filtrate concentrated to dryness
5. customThe residue was chromatographed on alumina