Methane → 4,5-Dihydroxy-2-nitrobenzeneacetonitrile

HRID 1440376Notes

Reaction equation

HRID 1440376 reaction equation
C.[N+:2]([C:5]1[CH:10]=[C:9]([O:11]CC2C=CC=CC=2)[C:8]([O:19]CC2C=CC=CC=2)=[CH:7][C:6]=1[CH2:27][C:28]#[N:29])([O-:4])=[O:3].C1CCCCC=1>[Pd].C(O)C>[N+:2]([C:5]1[CH:10]=[C:9]([OH:11])[C:8]([OH:19])=[CH:7][C:6]=1[CH2:27][C:28]#[N:29])([O-:4])=[O:3]

Participants

6

Reactant 3

HCID 297MethaneHCID 8079CyclohexeneHCID 10904838[4,5-Bis(benzyloxy)-2-nitrophenyl]acetonitrile

Product 1

HCID 109213934,5-Dihydroxy-2-nitrobenzeneacetonitrile

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

0.75 g of palladium at a concentration of 10% on charcoal, to which 3 g of charcoal have been added, followed by 0.02 mole (7.5 g) of 2-nitro-4,5-dibenzyloxyphenylacetonitrile, are added with stirring to 30 ml of 96° C. ethanol containing 15 ml of cyclohexene; the reaction mixture is heated under reflux for 1 hour.

Workup

  1. additionare added
  2. temperaturethe reaction mixture is heated
  3. temperatureunder reflux for 1 hour

Sources & evidence

ORD record
ord-4899053939e24cce8d7e8c75e621e982
Source dataset
uspto-grants-1996_03
Patent number
US05498746

Reaction notes

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