Tetrahydrofuran → 1-(4-aminobenzyl)-5,7-diethyl-1,6-naphthyridin-2(1H)-one

HRID 144213Notes

Reaction equation

HRID 144213 reaction equation
[CH2:1]([CH3:2])[c:3]1[c:4]2[cH:5][cH:6][c:7](=[O:25])[n:8]([CH2:15][c:16]3[cH:17][cH:18][c:19]([N+:22]([O-:23])=[O:24])[cH:20][cH:21]3)[c:9]2[cH:10][c:11]([CH2:13][CH3:14])[n:12]1.[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[Pt:31](=[O:32])=[O:33]>>[CH2:1]([CH3:2])[c:3]1[c:4]2[cH:5][cH:6][c:7](=[O:25])[n:8]([CH2:15][c:16]3[cH:17][cH:18][c:19]([NH2:22])[cH:20][cH:21]3)[c:9]2[cH:10][c:11]([CH2:13][CH3:14])[n:12]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 345198Adams' catalystHCID 189523915,7-diethyl-1-(4-nitrobenzyl)-1,6-naphthyridin-2(1H)-one

Product 1

HCID 189523881-(4-aminobenzyl)-5,7-diethyl-1,6-naphthyridin-2(1H)-one

Sources & evidence

ORD record
ord-777f98bb06374926beac1a1f45e37b37
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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