Dimethylformamide → 6-acetyl-9-(2-fluorobenzyl)-2-(2-fluorophenyl)-7,8,9,10-tetrahydro-imidazo[1,2-c]pyrido[3,4-e] pyrimidin-5(6H)-one

HRID 144364Notes

Reaction equation

HRID 144364 reaction equation
[CH3:30][C:31]([Cl:32])=[O:33].[CH3:39][CH2:40][O:41][C:42](=[O:43])[CH3:44].[F:1][c:2]1[c:3]([CH2:4][N:5]2[CH2:6][c:7]3[c:8]4[n:9]([c:10](=[O:15])[nH:11][c:12]3[CH2:13][CH2:14]2)[cH:16][c:17](-[c:19]2[c:20]([F:25])[cH:21][cH:22][cH:23][cH:24]2)[n:18]4)[cH:26][cH:27][cH:28][cH:29]1.[O:34]=[CH:35][N:36]([CH3:37])[CH3:38]>>[F:1][c:2]1[c:3]([CH2:4][N:5]2[CH2:6][c:7]3[c:8]4[n:9]([c:10](=[O:15])[n:11]([C:31]([CH3:30])=[O:33])[c:12]3[CH2:13][CH2:14]2)[cH:16][c:17](-[c:19]2[c:20]([F:25])[cH:21][cH:22][cH:23][cH:24]2)[n:18]4)[cH:26][cH:27][cH:28][cH:29]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 6367Acetyl chlorideHCID 8857Ethyl AcetateHCID 11761005HCID 11761005, compound

Product 1

HCID 190143566-acetyl-9-(2-fluorobenzyl)-2-(2-fluorophenyl)-7,8,9,10-tetrahydro-imidazo[1,2-c]pyrido[3,4-e] pyrimidin-5(6H)-one

Sources & evidence

ORD record
ord-64433638788f48598d7c3cf003f68e50
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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