Chloride → [3-(4-Bromo-phenyl)-3-(4-chloro-phenyl)-propyl]methyl-amine

HRID 144366Notes

Reaction equation

[Al+3:22].[Al+3:28].[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][C:10](=[O:11])[NH:12][CH3:13])[c:14]2[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[cH:6][cH:7]1.[CH3:31][CH2:32][O:33][CH2:34][CH3:35].[Cl-:27].[Cl-:29].[Cl-:30].[H-:21].[H-:24].[H-:25].[H-:26].[Li+:23]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][CH2:10][NH:12][CH3:13])[c:14]2[cH:15][cH:16][c:17]([Cl:20])[cH:18][cH:19]2)[cH:6][cH:7]1

Participants

Reactant 6

HCID 312Chloride3×

HCID 3283Diethyl Ether

HCID 28486Lithium ion

HCID 104727Aluminum Cation2×

HCID 166653Hydride4×

HCID 593319703-(4-Bromo-phenyl)-3-(4-chloro-phenyl)-N-methyl-propionamide

Product 1

HCID 59331923[3-(4-Bromo-phenyl)-3-(4-chloro-phenyl)-propyl]methyl-amine

Sources & evidence

ORD record: ord-583b8bb6e53b4fde866dcf3bc2c9d4b2
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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