Propargyl alcohol → HCID 10309050, compound

HRID 1444066Notes

Reaction equation

HRID 1444066 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[S:9]([NH:12][C:13]1[C:18](Cl)=[N:17][CH:16]=[CH:15][N:14]=1)(=[O:11])=[O:10].[H-].[Na+].[CH2:22]([OH:25])[C:23]#[CH:24]>>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[S:9]([NH:12][C:13]1[C:18]([O:25][CH2:22][C:23]#[CH:24])=[N:17][CH:16]=[CH:15][N:14]=1)(=[O:11])=[O:10]

Participants

4

Reactant 3

HCID 7859Propargyl alcoholHCID 24758Sodium hydrideHCID 591681672,3-Dichloro-N-(3-chloro-2-pyrazinyl)benzenesulphonamide

Product 1

HCID 10309050HCID 10309050, compound

Procedure

Prepared by the method of Example 28 using propargyl alcohol as solvent (3 mL), 2,3-dichloro-N-(3-chloro-2-pyrazinyl)benzenesulphonamide (Example 28) (0.3 g) and sodium hydride (0.2 g of a 60% dispersion in oil) at room temperature for 16 h. Yield 0.27 g.

Sources & evidence

ORD record
ord-cbaaebce16204488855405321111808b
Source dataset
uspto-grants-2010_02
Patent number
US07662825B2

Reaction notes

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