反应详情

Methyl ester (16) (500 mg, 1.48 mmol) was coupled to phenylboronic acid (150 mg, 1.23 mmol) using Method E. The crude compound was purified by column chromatography, eluting with a stepped gradient of 20-25% EtOAc in heptane to give the title compound.

1. customThe crude compound was purified by column chromatography
2. washeluting with a stepped gradient of 20-25% EtOAc in heptane