反应详情

温度

85 °C

3-(5-Ammoniopentanoyl)pyridinium chloride (219 mg, 0.87 mmol) and 3-formylchromone (228 mg, 1.31 mmol) were combined and suspended in a reaction vessel with i-propanol (30 mL). The reaction vessel was sealed and the reaction heated to 85 ° C. overnight then cooled to room temperature. The precipitate was recovered by vacuum filtration, washed with a 20% i-propanol in hexane solution, then dried under vacuum giving 245 mg (72%) of a powdery brown solid. LC-MS: RT=4.20 min, [M+H]+=317.1.

1. customThe reaction vessel was sealed
2. temperaturethen cooled to room temperature
3. filtrationThe precipitate was recovered by vacuum filtration
4. washwashed with a 20% i-propanol in hexane solution
5. customdried under vacuum