Hydrochloric Acid → HCID 67142041, compound

HRID 1445124Notes

Reaction equation

HRID 1445124 reaction equation
[CH2:1]([N:8]1[C:12]2=[C:13]([NH:20][CH2:21][C:22]3[CH:27]=[CH:26][C:25]([F:28])=[CH:24][CH:23]=3)[N:14]=[C:15]([C:17]([OH:19])=[O:18])[CH:16]=[C:11]2[C:10]([CH3:29])=[C:9]1[CH3:30])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:31]>C(OCC)(=O)C>[ClH:31].[CH2:1]([N:8]1[C:12]2=[C:13]([NH:20][CH2:21][C:22]3[CH:23]=[CH:24][C:25]([F:28])=[CH:26][CH:27]=3)[N:14]=[C:15]([C:17]([OH:19])=[O:18])[CH:16]=[C:11]2[C:10]([CH3:29])=[C:9]1[CH3:30])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 67142042HCID 67142042, compound

Product 1

HCID 67142041HCID 67142041, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A solution of 1-benzyl-7-(4-fluorobenzylamino)-2,3-dimethyl-1H-pyrrolo[2,3-c]pyridin-5-carboxylic acid prepared in Step 1 in ethyl acetate was saturated with hydrochloric acid gas and then filtered to give 10.5 mg of the titled compound as a white solid.

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-a84bd136b49641819e2ecfbe840ea591
Source dataset
uspto-grants-2010_02
Patent number
US07662832B2

Reaction notes

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