Hydrochloric Acid → 4-Benzyl-1,2,4-thiadiazolidine-3,5-dione

HRID 1445677Notes

Reaction equation

[CH2:1]([N:8]=[C:9]=[S:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[O-:12][Mn](=O)(=O)=O.[K+].[N:18](C(OCC)=O)=[C:19]=[O:20]>>[CH2:1]([N:8]1[C:9](=[O:12])[S:10][NH:18][C:19]1=[O:20])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 4

HCID 313Hydrochloric Acid

HCID 2346Benzyl Isothiocyanate

HCID 300166ethyl N-carbonylcarbamate

HCID 516875Potassium Permanganate

Product 1

HCID 225072054-Benzyl-1,2,4-thiadiazolidine-3,5-dione

Procedure

Reagents: Benzyl isothiocyanate (0.81 ml, 6.5 mmol), 35% HCl (3.1 ml), KMnO4 (0.5 g), ethyl isocyanatoformate (0.69 ml, 6.5 mmol).

Sources & evidence

ORD record: ord-fdcd7e2198134da491b02f68fc216676
Source dataset: uspto-grants-2010_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07666885B2

Reaction notes

Loading…