Hydrochloric Acid → N-(4-(Methylsulfonyl)benzyl)-7-(4-(2-(pyridin-2-yl)ethyl)piperazin-1-yl)benzofuran-2-carboxamide

HRID 144615Notes

Reaction equation

HRID 144615 reaction equation
[CH3:29][S:30](=[O:31])(=[O:32])[c:33]1[cH:34][cH:35][c:36]([CH2:37][NH2:38])[cH:39][cH:40]1.[ClH:28].[Li+:27].[n:1]1[c:2]([CH2:7][CH2:8][N:9]2[CH2:10][CH2:11][N:12]([c:15]3[cH:16][cH:17][cH:18][c:19]4[cH:20][c:21]([C:24](=[O:25])[O-:26])[o:22][c:23]34)[CH2:13][CH2:14]2)[cH:3][cH:4][cH:5][cH:6]1>>[n:1]1[c:2]([CH2:7][CH2:8][N:9]2[CH2:10][CH2:11][N:12]([c:15]3[cH:16][cH:17][cH:18][c:19]4[cH:20][c:21]([C:24](=[O:25])[NH:38][CH2:37][c:36]5[cH:35][cH:34][c:33]([S:30]([CH3:29])(=[O:31])=[O:32])[cH:40][cH:39]5)[o:22][c:23]34)[CH2:13][CH2:14]2)[cH:3][cH:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 28486Lithium ionHCID 574214-MethylsulfonylbenzylamineHCID 596367367-[4-(2-Pyridin-2-ylethyl)piperazin-1-yl]-1-benzofuran-2-carboxylate

Product 1

HCID 59636750N-(4-(Methylsulfonyl)benzyl)-7-(4-(2-(pyridin-2-yl)ethyl)piperazin-1-yl)benzofuran-2-carboxamide

Sources & evidence

ORD record
ord-ae64e8e245b04b7c88d0fd6860ccb83c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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