Diethylamine → HCID 24809893, compound

HRID 1446168Notes

Reaction equation

HRID 1446168 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[O:13][N:12]=[CH:11][C:10]=2[C:14]([OH:16])=O)=[CH:5][CH:4]=1.[CH2:17]([NH:19][CH2:20][CH3:21])[CH3:18]>>[CH2:17]([N:19]([CH2:20][CH3:21])[C:14]([C:10]1[CH:11]=[N:12][O:13][C:9]=1[C:6]1[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=1)=[O:16])[CH3:18]

Participants

3

Reactant 2

HCID 8021DiethylamineHCID 49979625-(4-methoxyphenyl)isoxazole-4-carboxylic acid

Product 1

HCID 24809893HCID 24809893, compound

Procedure

The title compound was prepared from 5-(4-methoxyphenyl)isoxazole-4-carboxylic acid (11.0 mg, 0.050 mmol) and diethylamine (4.4 mg, 0.060 mmol) as described in synthetic method A and thereafter purified by preparative HPLC method A to give a solid (7.8 mg). MS (pos) m/z 275.2 (M+1).

Workup

  1. custompurified by preparative HPLC method A

Sources & evidence

ORD record
ord-8f7719f51ed94467ba33c9c77e26054e
Source dataset
uspto-grants-2010_02
Patent number
US07666888B2

Reaction notes

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