1H-1,2,4-Triazole → HCID 4184330, compound

HRID 1447013Notes

Reaction equation

HRID 1447013 reaction equation
[NH:1]1[CH:5]=[N:4][CH:3]=[N:2]1.C(=O)([O-])[O-].[K+].[K+].[CH2:12](Cl)[CH:13]=[CH:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>C(#N)C>[C:15]1([CH:14]=[CH:13][CH2:12][N:1]2[CH:5]=[N:4][CH:3]=[N:2]2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

5

Reactant 3

HCID 92571H-1,2,4-TriazoleHCID 11430Potassium CarbonateHCID 94242Benzene, (3-chloro-1-propenyl)-

Product 1

HCID 4184330HCID 4184330, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A mixture of 14 parts by weight of 1,2,4-triazole, 200 parts by weight of acetonitrile, 32 parts by weight of potassium carbonate and 39.2 parts by weight of cinnamyl chloride is stirred for 12 hours, and then filtered. The filtrate is concentrated, dissolved in dichloromethane, washed with water, evaporated and distilled. There is obtained 26 parts by weight of 1-(3-phenyl-2-propenyl)-1,2,4-triazole; b.p. (0.27 mbar): 130°-134° C.

Workup

  1. filtrationfiltered
  2. concentrationThe filtrate is concentrated
  3. dissolutiondissolved in dichloromethane
  4. washwashed with water
  5. customevaporated
  6. distillationdistilled

Sources & evidence

ORD record
ord-a4450b6beda144c1bf1e5a9464fb75f2
Source dataset
uspto-grants-1982_02
Patent number
US04315017

Reaction notes

Loading…