3-Phenylprop-2-enoyl chloride → HCID 57198396, compound

HRID 1447167Notes

Reaction equation

HRID 1447167 reaction equation
[CH:1]1[N:9]2[C:4]([NH:5][NH:6][C:7]3[CH:13]=[CH:12][CH:11]=[CH:10][C:8]=32)=[N:3][N:2]=1.[C:14](Cl)(=[O:23])[CH:15]=[CH:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>CN(C)C=O>[C:14]([N:5]1[C:4]2=[N:3][N:2]=[CH:1][N:9]2[C:8]2[CH:10]=[CH:11][CH:12]=[CH:13][C:7]=2[N:6]1[C:14](=[O:23])[CH:15]=[CH:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)(=[O:23])[CH:15]=[CH:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

4

Reactant 2

HCID 660233-Phenylprop-2-enoyl chlorideHCID 135503117HCID 135503117, compound

Product 1

HCID 57198396HCID 57198396, compoundYield 75%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 4.0 g (0.023 mole) of 4,5-dihydro-s-triazolo[3,4-c]benzo-as-triazine, 7.66 g (0.046 mole) of cinnamoyl chloride and 70 ml of dimethyl formamide is refluxed for 4 hours, and the mixture is processed in the usual way. 7.48 g (75%) of the title compound are obtained; m.p.: 220°-221° C.

Workup

  1. temperatureis refluxed for 4 hours

Sources & evidence

ORD record
ord-1995b30f04a949829db8a5dc97f8efee
Source dataset
uspto-grants-1982_02
Patent number
US04316022

Reaction notes

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