Methyl chloroformate → HCID 20551614, compound

HRID 1447199Notes

Reaction equation

HRID 1447199 reaction equation
C(N(CC)CC)C.[CH3:8][C:9]1[C:25]([CH3:26])=[CH:24][CH:23]=[CH:22][C:10]=1[O:11][C:12]1[C:16]([C:17]([O:19][CH3:20])=[O:18])=[C:15]([CH3:21])[NH:14][N:13]=1.[C:27](Cl)(=[O:30])[O:28][CH3:29]>O1CCCC1>[CH3:29][O:28][C:27]([N:14]1[C:15]([CH3:21])=[C:16]([C:17]([O:19][CH3:20])=[O:18])[C:12]([O:11][C:10]2[CH:22]=[CH:23][CH:24]=[C:25]([CH3:26])[C:9]=2[CH3:8])=[N:13]1)=[O:30]

Participants

5

Reactant 3

HCID 6586Methyl chloroformateHCID 8471TriethylamineHCID 178498938HCID 178498938, compound

Product 1

HCID 20551614HCID 20551614, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A mixture of 5.6 g of triethylamine, 13 g of 3-(2',3'-dimethylphenoxy)-5-methyl-4-methoxycarbonyl pyrazole and 100 ml of tetrahydrofuran is prepared, and, while stirring and cooling, 4.9 g of methyl chlorocarbonate is dripped in. After stirring for 16 hours, the precipitated hydrochloride is filtered off. The filtrate is concentrated and the residue is recrystallized from ethyl acetate. Melting point: 115° C.

Workup

  1. customis prepared
  2. temperaturecooling
  3. stirringAfter stirring for 16 hours
  4. filtrationthe precipitated hydrochloride is filtered off
  5. concentrationThe filtrate is concentrated
  6. customthe residue is recrystallized from ethyl acetate

Sources & evidence

ORD record
ord-937645f1f31549c49361cbf6135b4941
Source dataset
uspto-grants-1982_02
Patent number
US04316040

Reaction notes

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