Trifluoroacetic acid → HCID 86738262, compound

HRID 1447300Notes

Reaction equation

HRID 1447300 reaction equation
C([CH:3]([CH2:7][CH2:8][CH2:9][CH3:10])[C:4]([OH:6])=[O:5])C.[F:11][C:12]([F:17])([F:16])[C:13]([OH:15])=[O:14].[OH-].[Na+].O.O.O.O.O.O.O.S([O-])([O-])(=O)=O.[Ni+2:32]>CO>[F:11][C:12]([F:17])([F:16])[C:13]([O-:15])=[O:14].[C:4]([O:6][CH2:12][CH3:13])(=[O:5])[CH2:3][CH2:7][CH2:8][CH2:9][CH3:10].[Ni+2:32].[F:11][C:12]([F:17])([F:16])[C:13]([O-:15])=[O:14]

Participants

6

Reactant 4

HCID 6422Trifluoroacetic acidHCID 86972-Ethylhexanoic AcidHCID 14798Sodium HydroxideHCID 61474Nickel sulfate heptahydrate

Product 1

HCID 86738262HCID 86738262, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

14.4 g of 2-ethyl hexanoic acid (0.1 mole), 100 cm3 of methanol, 11.4 g of trifluoroacetic acid (0.1 mole) and 8.0 g of sodium hydroxide (0.2 mole) are successively fed into a 500 cm3 glass reaction vessel provided with a magnetic stirring rod and a reflux device. The mixture is heated to reflux and 35.1 g (0.125 mole) of nickel sulfate heptahydrate is added. The mixture is heated again at reflux. Methanol is evaporated by means of a rotary evaporator and the residue is taken up in toluene. After filtration of the insoluble inorganic salts, toluene is distilled off and nickel 2-ethyl hexanoate trifluoroacetate is obtained. Its analysis corresponds to the formula C10H15O4F3Ni and it has the same characteristic bands as the product of example 1.

Workup

  1. customprovided with a magnetic stirring rod
  2. temperatureThe mixture is heated
  3. temperatureto reflux
  4. temperatureThe mixture is heated again
  5. temperatureat reflux
  6. customMethanol is evaporated by means of a rotary evaporator
  7. filtrationAfter filtration of the insoluble inorganic salts, toluene
  8. distillationis distilled off

Sources & evidence

ORD record
ord-5626f323e4504b18a74e2de53d28b4e4
Source dataset
uspto-grants-1982_02
Patent number
US04316851

Reaction notes

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