Dimethylformamide → 4-(2-Fluoro-4-methanesulfonyl-phenoxy)-5-methyl-6-[1-(2-pyridin-3-yl-ethyl)-piperidin-4-yloxy]-pyrimidine
Reaction equation
[CH3:46][CH2:47][N:48]([CH2:49][CH3:50])[CH2:51][CH3:52].[F:1][c:2]1[c:3]([O:4][c:5]2[n:6][cH:7][n:8][c:9]([O:12][CH:13]3[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]3)[c:10]2[CH3:11])[cH:19][cH:20][c:21]([S:23](=[O:24])(=[O:25])[CH3:26])[cH:22]1.[O:53]=[CH:54][N:55]([CH3:56])[CH3:57].[n:27]1[cH:28][c:29]([CH2:33][CH2:34][O:35][S:36]([c:37]2[cH:38][cH:39][c:40]([CH3:41])[cH:42][cH:43]2)(=[O:44])=[O:45])[cH:30][cH:31][cH:32]1>>[F:1][c:2]1[c:3]([O:4][c:5]2[n:6][cH:7][n:8][c:9]([O:12][CH:13]3[CH2:14][CH2:15][N:16]([CH2:34][CH2:33][c:29]4[cH:28][n:27][cH:32][cH:31][cH:30]4)[CH2:17][CH2:18]3)[c:10]2[CH3:11])[cH:19][cH:20][c:21]([S:23](=[O:24])(=[O:25])[CH3:26])[cH:22]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-e8d10c8f590f487b84c49cc0fd1ce05b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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