Hydrochloric Acid → HCID 20380297, compound

HRID 1448592Notes

Reaction equation

HRID 1448592 reaction equation
[C:1]1([OH:13])[CH:12]=[C:6]([CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])[CH:5]=[C:3]([OH:4])[CH:2]=1.[CH3:14][N:15]1[CH2:20][CH2:19][C:18](=O)[CH2:17][CH2:16]1.[ClH:22]>C(O)(=O)C>[ClH:22].[CH3:14][N:15]1[CH2:16][CH:17]=[C:18]([C:2]2[C:3]([OH:4])=[CH:5][C:6]([CH2:7][CH2:8][CH2:9][CH2:10][CH3:11])=[CH:12][C:1]=2[OH:13])[CH2:19][CH2:20]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 10377OlivetolHCID 740491-Methyl-4-piperidone

Product 1

HCID 20380297HCID 20380297, compoundYield 79%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Olivetol (22.3 g) and N-methyl-4 -piperidone (14 g) were dissolved in 50 ml acetic acid and treated with HCl gas as described in Example VI giving 30.6 g (79%) product, m.p. 179°-180°.

Sources & evidence

ORD record
ord-d040a3be0e594d5b8bdb07288ab11c6c
Source dataset
uspto-grants-1979_12
Patent number
US04180669

Reaction notes

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