Acetate → N-[2-(3-cyanoazetidin-1-yl)-1-cyclopropyl-2-oxoethyl]-2-[4-(trifluoromethyl)phenyl]-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide
Reaction equation
[C:1](#[N:2])[CH:3]1[CH2:4][N:5]([C:7]([CH:8]([CH:9]2[CH2:10][CH2:11]2)[NH:12][C:13](=[O:14])[c:15]2[cH:16][n:17]([CH2:34][O:35][CH2:36][CH2:37][Si:38]([CH3:39])([CH3:40])[CH3:41])[c:18]3[n:19][cH:20][c:21](-[c:24]4[cH:25][cH:26][c:27]([C:30]([F:31])([F:32])[F:33])[cH:28][cH:29]4)[n:22][c:23]23)=[O:42])[CH2:6]1.[CH3:51][C:52](=[O:53])[O-:54].[CH3:59][CH2:60][O:61][C:62](=[O:63])[CH3:64].[Cl:56][CH2:57][Cl:58].[Na+:50].[OH2:55].[OH:43][C:44]([C:45]([F:46])([F:47])[F:48])=[O:49]>>[C:1](#[N:2])[CH:3]1[CH2:4][N:5]([C:7]([CH:8]([CH:9]2[CH2:10][CH2:11]2)[NH:12][C:13](=[O:14])[c:15]2[cH:16][nH:17][c:18]3[n:19][cH:20][c:21](-[c:24]4[cH:25][cH:26][c:27]([C:30]([F:31])([F:32])[F:33])[cH:28][cH:29]4)[n:22][c:23]23)=[O:42])[CH2:6]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-23451475b9e44aa1af8e9e4045b085ec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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