Sodium Bicarbonate → HCID 23666533, compound

HRID 1448837Notes

Reaction equation

HRID 1448837 reaction equation
C(=O)([O-])O.[Na+:5].[CH2:6]([N:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[C:16]([CH:23]([CH3:27])[C:24]([OH:26])=[O:25])=[CH:15][C:14]1=[O:28])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>O>[CH2:6]([N:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[C:16]([CH:23]([CH3:27])[C:24]([O-:26])=[O:25])=[CH:15][C:14]1=[O:28])[C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1.[Na+:5]

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 12802755HCID 12802755, compound

Product 1

HCID 23666533HCID 23666533, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

An aqueous solution (1.63 ml.) of 1 M-sodium hydrogen carbonate was added to a stirred suspension of powdered α-(1-benzyl-1,2-dihydro-2-oxoquinol-4-yl)propionic acid (0.50 g.) in distilled water (3.37 ml.), and the mixture was stirred overnight, at ambient temperature. The solid which had formed was separated and dried in vacuo over phosphorus pentoxide to give sodium α-(1-benzyl-1,2-dihydro-2-oxoquinol-4-yl)-propionate (0.52 g.) as its monohydrate (m.p., indefinite;

Workup

  1. customThe solid which had formed
  2. customwas separated
  3. dry with materialdried in vacuo over phosphorus pentoxide

Sources & evidence

ORD record
ord-6091c47631c34150b1d858a497ab9310
Source dataset
uspto-grants-1980_02
Patent number
US04187310

Reaction notes

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