HRID1449002

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14273

2-Pyridinecarboxaldehyde

C6H5NO

HCID643756

未命名化合物

HCID11480907

ethyl 4-acetoxyacetoacetate

C8H12O5

PRODUCTS

生成物

结构：CCOC(=O)C1=C(C)NC(COC(C)=O)=C(C(=O)OCC)C1c1ccccn1

HCID70590562

未命名化合物

收率 60%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

A solution of 5.4 g of pyridine-2-aldehyde, 9.4 g of γ-acetoxyacetoacetic acid ethyl ester and 6.5 g of β-aminocrotonic acid ethyl ester in 40 ccs of ethanol is heated to the boil overnight and then cooled. After filtering, beige crystals of melting point 116° C. are obtained, yield: 60%.

WORKUP

后处理

temperaturecooled
filtrationAfter filtering
custombeige crystals of melting point 116° C. are obtained