Glycinamide → 2-[3-(2-Chloro-6-methylphenyl)-thioureido]-acetamide

HRID 1449606Notes

Reaction equation

HRID 1449606 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[N:9]=[C:10]=[S:11].[NH2:12][CH2:13][C:14]([NH2:16])=[O:15]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][C:10](=[S:11])[NH:12][CH2:13][C:14]([NH2:16])=[O:15]

Participants

3

Reactant 2

HCID 69020GlycinamideHCID 37317252-Chloro-6-Methylphenyl Isothiocyanate

Product 1

HCID 543940602-[3-(2-Chloro-6-methylphenyl)-thioureido]-acetamide

Procedure

2-[3-(2-Chloro-6-methylphenyl)-thioureido]-acetamide was prepared by the procedure described in Example 2 using 18.3 g of 2-chloro-6-methylphenylisothiocyanate and 12.0 g of glycinamide. 22.8 Grams of the product was obtained, m.p. 161°-163° C. (dec.). This compound was used without further purification in the next paragraph.

Workup

  1. custom22.8 Grams of the product was obtained
  2. customThis compound was used without further purification in the next paragraph

Sources & evidence

ORD record
ord-ce21785bce2a4cc4b0c6bb0b05db383f
Source dataset
uspto-grants-1997_02
Patent number
US05599829

Reaction notes

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