Acetic Acid → 1,1-Dimethylethyl 4-(2-thiazolylamino)-1-piperidinecarboxylate

HRID 145027Notes

Reaction equation

HRID 145027 reaction equation
[C:21]([O:22][BH-:23]([O:24][C:25](=[O:26])[CH3:27])[O:28][C:29](=[O:30])[CH3:31])(=[O:32])[CH3:33].[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH3:35][C:36](=[O:37])[OH:38].[NH2:1][c:2]1[s:3][cH:4][cH:5][n:6]1.[NH2:7][CH:8]1[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]1.[Na+:34]>>[NH:1]([c:2]1[s:3][cH:4][cH:5][n:6]1)[CH:8]1[CH2:9][CH2:10][N:11]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:12][CH2:13]1

Participants

7

Reactant 6

HCID 176Acetic AcidHCID 923Sodium ionHCID 21552-AminothiazoleHCID 8028TetrahydrofuranHCID 12682914-Amino-1-Boc-piperidineHCID 2724942Triacetoxyborohydride

Product 1

HCID 231309421,1-Dimethylethyl 4-(2-thiazolylamino)-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-8a8faaec35154866858d44194846d6d8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…