Water → HCID 86750337, compound

HRID 1450308Notes

Reaction equation

HRID 1450308 reaction equation
[OH-].[OH:2][P:3]([O:12][CH2:13][CH:14]1[CH2:18][CH:17]([S:19][C:20]2[CH:26]([CH3:27])[CH:25]3[N:22]([C:23](=[O:31])[CH:24]3[CH:28]([OH:30])[CH3:29])[C:21]=2[C:32]([O:34]CC2C=CC([N+]([O-])=O)=CC=2)=[O:33])[CH2:16][O:15]1)([O:5]C([N+](C)(C)C)C)=[O:4].C(=O)(O)[O-].[Na+].O.O1[CH2:56][CH2:55]OCC1>[Pd]>[OH-:2].[C:32]([C:21]1[N:22]2[CH:25]([CH:26]([CH3:27])[C:20]=1[S:19][CH:17]1[CH2:16][O:15][CH:14]([CH2:13][O:12][P:3]([OH:2])([O:5][CH2:55][CH2:56][N+:22]([CH3:25])([CH3:23])[CH3:21])=[O:4])[CH2:18]1)[CH:24]([CH:28]([OH:30])[CH3:29])[C:23]2=[O:31])([OH:34])=[O:33]

Participants

6

Reactant 4

HCID 962WaterHCID 312751,4-DioxaneHCID 516892Sodium BicarbonateHCID 86750339HCID 86750339, compound

Product 1

HCID 86750337HCID 86750337, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The title compound is prepared by the procedure of Example 18 using 0.387 g of product from Example 91, 0.046 g of sodium bicarbonate, 4 ml of water, 19 ml of dioxane, and 0.050 g of 10% palladium/carbon to give 0.031 g of the desired product.

Sources & evidence

ORD record
ord-997da81dbcc447479de744411e7c8830
Source dataset
uspto-grants-1997_02
Patent number
US05602118

Reaction notes

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