Hydrochloric Acid → 1-[1-(3-Tert-butoxy-2-pyrazinylmethyl)piperidin-4-yl]-2-[2-(trifluoromethyl)phenyl]ethanone
Reaction equation
[C:21]([CH3:22])([CH3:23])([CH3:24])[O:25][c:26]1[c:27]([CH:32]=[O:33])[n:28][cH:29][cH:30][n:31]1.[C:34]([O:35][BH-:36]([O:37][C:38](=[O:39])[CH3:40])[O:41][C:42](=[O:43])[CH3:44])(=[O:45])[CH3:46].[CH3:53][CH2:54][O:55][C:56](=[O:57])[CH3:58].[Cl:50][CH2:51][Cl:52].[ClH:1].[NH:2]1[CH2:3][CH2:4][CH:5]([C:8]([CH2:9][c:10]2[c:11]([C:16]([F:17])([F:18])[F:19])[cH:12][cH:13][cH:14][cH:15]2)=[O:20])[CH2:6][CH2:7]1.[Na+:47].[Na+:49].[OH-:48]>>[N:2]1([CH2:32][c:27]2[c:26]([O:25][C:21]([CH3:22])([CH3:23])[CH3:24])[n:31][cH:30][cH:29][n:28]2)[CH2:3][CH2:4][CH:5]([C:8]([CH2:9][c:10]2[c:11]([C:16]([F:17])([F:18])[F:19])[cH:12][cH:13][cH:14][cH:15]2)=[O:20])[CH2:6][CH2:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-74a4b8fdf8674d809d8d60df207a7627
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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