Hydrochloric Acid → HCID 178447452, compound

HRID 1450516Notes

Reaction equation

HRID 1450516 reaction equation
[NH:1]1[C:5]([C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[OH:12])=[N:4][N:3]=[N:2]1.[C:13](Cl)(=[O:18])[C:14]([CH3:17])([CH3:16])[CH3:15].Cl>N1C=CC=CC=1>[C:13]([O:12][C:7]1[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=1[C:5]1[NH:1][N:2]=[N:3][N:4]=1)(=[O:18])[C:14]([CH3:17])([CH3:16])[CH3:15]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 62493Pivaloyl chlorideHCID 178515941HCID 178515941, compound

Product 1

HCID 178447452HCID 178447452, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

2-(1H-Tetrazol-5-yl)phenol (4.86 g) was dissolved in pyridine (20 ml), and pivaloyl chloride (7.2 g) was added to the solution at room temperature. After being stirred for 15 h, the mixture was poured into ice water and acidified with dilute hydrochloric acid. The resulting crystals were collected by filtration and dried to give the title compound.

Workup

  1. filtrationThe resulting crystals were collected by filtration
  2. customdried

Sources & evidence

ORD record
ord-cf1d4f3f3b2a4145a0a37baf75fff3d2
Source dataset
uspto-grants-1997_02
Patent number
US05602161

Reaction notes

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