Ethanol → HCID 3545503, compound

HRID 1451142Notes

Reaction equation

HRID 1451142 reaction equation
[C:1]1([NH:7][NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:9]([C:13]1[CH:20]=[CH:19][C:16]([CH:17]=O)=[CH:15][CH:14]=1)([CH3:12])([CH3:11])[CH3:10].C(O)C>CO>[C:1]1([NH:7][N:8]=[CH:17][C:16]2[CH:19]=[CH:20][C:13]([C:9]([CH3:12])([CH3:11])[CH3:10])=[CH:14][CH:15]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 7516PhenylhydrazineHCID 703244-tert-Butylbenzaldehyde

Product 1

HCID 3545503HCID 3545503, compoundYield 93.1%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In 20 ml of methanol was dissolved 2.18 g of phenylhydrazine. While metering, 3.24 g of 4-tert-butylbenzaldehyde was added dropwise to the solution. Reaction quickly took place. With heat release, the entire solution solidified. 5 ml of ethanol was added to the mass and the crystals were washed and collected by suction filtration. The crystals were washed with a small amount of methanol and dried in vacuum for 1.5 hours, obtaining 4.69 g (yield 93%) of pale yellow crystals.

Workup

  1. customReaction quickly took place
  2. temperatureWith heat release
  3. washthe crystals were washed
  4. filtrationcollected by suction filtration
  5. washThe crystals were washed with a small amount of methanol
  6. customdried in vacuum for 1.5 hours

Sources & evidence

ORD record
ord-a354af9635e543c6ad8654bf070092bb
Source dataset
uspto-grants-1997_02
Patent number
US05604004

Reaction notes

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