反应详情

温度

100 °C

A mixture of Furo[3,4-c]quinoline-1,3,4(5H)-trione (215 mg) and aniline (93 mg) in dry dimethylformamide (3 mL) was heated at 100° C. for 5 min. After coolong to room temperature 1,1'-Carbonyldiimidazole (200 mg) was added. The reaction mixture was then heated again to 100° C. for an additional 5 min. After cooling the reaction mixture was poured onto water to afford 2-Phenyl-pyrrolo[3,4-c]quinoline-1,3,4(5H)-trione (Compound 1) as yellow crystals melting at >390° C.

1. customAfter coolong to room temperature
2. additionwas added
3. temperatureThe reaction mixture was then heated again to 100° C. for an additional 5 min
4. temperatureAfter cooling the reaction mixture
5. additionwas poured onto water