Hydrochloric Acid → HCID 68821142, compound

HRID 1453539Notes

Reaction equation

HRID 1453539 reaction equation
[BH4-].[Na+].[CH3:3][N:4]1[C:9]2[S:10][CH:11]=[C:12]([CH3:13])[C:8]=2[S:7](=[O:15])(=[O:14])[N:6]=[CH:5]1.Cl>C(O)(C)C.O>[CH3:3][N:4]1[C:9]2[S:10][CH:11]=[C:12]([CH3:13])[C:8]=2[S:7](=[O:15])(=[O:14])[NH:6][CH2:5]1

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 4311764Sodium borohydrideHCID 68821354HCID 68821354, compound

Product 1

HCID 68821142HCID 68821142, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 3776IsopropanolSolvent

Conditions

Temperature
50 °C

Procedure

240 mg of sodium borohydride are added to 120 mg of the compound obtained in Step B above dissolved in 6 ml of isopropanol. The mixture is heated at 50° C. for 10 minutes. The solvent is removed under reduced pressure, then the residue that is obtained is taken up in 5 ml of water. The pH of the solution is adjusted to 4 by addition of 6N hydrochloric acid. The precipitate is collected by filtration, washed with water and dried.

Workup

  1. customThe solvent is removed under reduced pressure
  2. customthe residue that is obtained
  3. filtrationThe precipitate is collected by filtration
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-1e0c8f53fcb549ba97834d9fd9464be4
Source dataset
uspto-grants-2009_01
Patent number
US07476668B2

Reaction notes

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