Dimethylformamide dimethyl acetal → 51519-09-6

HRID 1454800Notes

Reaction equation

HRID 1454800 reaction equation
[NH2:1][C:2]1[CH:7]=[N:6][CH:5]=[CH:4][N:3]=1.CO[CH:10](OC)[N:11]([CH3:13])[CH3:12]>>[CH3:10][N:11]([CH3:13])[CH:12]=[N:1][C:2]1[CH:7]=[N:6][CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 78747Aminopyrazine

Product 1

HCID 1222947551519-09-6

Procedure

A solution of 2-aminopyrazine (16.45 g) in dimethylformamide dimethylacetal (22.4 g) was refluxed at 85° C. for 3 h, evaporated under reduced pressure, and used in the next step without further purification.

Workup

  1. customevaporated under reduced pressure
  2. customused in the next step without further purification

Sources & evidence

ORD record
ord-f0e41c090fba493da97c1f7fcb804e13
Source dataset
uspto-grants-2009_01
Patent number
US07482336B2

Reaction notes

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