Hydrochloric Acid → (+/-)-6-({[(3-fluoro-1-{2-[3-fluoro-6-(methyloxy)-1,5-naphthyridin-4-yl]ethyl}-3-pyrrolidinyl)methyl]amino}methyl)-2H-pyrido[3,2-b][1,4]thiazin-3(4H)-one
Reaction equation
[BH4-:52].[CH3:1][C:2]([N:5]([C:3](=[O:4])[O-:6])[CH2:9][C:10]1([F:30])[CH2:11][N:12]([CH2:15][CH2:16][c:17]2[c:18]([F:29])[cH:19][n:20][c:21]3[cH:22][cH:23][c:24]([O:27][CH3:28])[n:25][c:26]23)[CH2:13][CH2:14]1)([CH3:7])[CH3:8].[CH3:45][CH2:46][N:47]([CH2:48][CH3:49])[CH2:50][CH3:51].[CH3:63][CH2:64][OH:65].[Cl:60][CH2:61][Cl:62].[ClH:31].[Na+:53].[O:32]=[C:33]1[CH2:34][S:35][c:36]2[c:37]([n:39][c:40]([CH:43]=[O:44])[cH:41][cH:42]2)[NH:38]1.[O:54]1[CH2:55][CH2:56][O:57][CH2:58][CH2:59]1>>[NH:5]([CH2:9][C:10]1([F:30])[CH2:11][N:12]([CH2:15][CH2:16][c:17]2[c:18]([F:29])[cH:19][n:20][c:21]3[cH:22][cH:23][c:24]([O:27][CH3:28])[n:25][c:26]23)[CH2:13][CH2:14]1)[CH2:43][c:40]1[n:39][c:37]2[c:36]([cH:42][cH:41]1)[S:35][CH2:34][C:33](=[O:32])[NH:38]2Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-631633e2a27b404d859da7bf74a68e87
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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