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HRID1455646

反应详情

EQUATION

反应方程式

HRID 1455646 的结构方程式

REACTANTS

反应物

4
结构：COCCOC
HCID8071

未命名化合物

结构：[Cs+].[F-]
HCID25953

Cesium fluoride

CsF

结构：CSc1ccc(B(O)O)cc1
HCID2733959

4-(Methylthio)phenylboronic acid

C7H9BO2S

结构：COC(=O)c1ccc(N)c(I)c1
HCID4104649

Methyl 4-amino-3-iodobenzoate

C8H8INO2

PRODUCTS

生成物

1
结构：COC(=O)c1ccc(N)c(-c2ccc(SC)cc2)c1
HCID68952232

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CCCCCC
溶剂HCID8058

n-Hexane

C6H14

结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

Prepared according to the general procedure Coupling-1 (CsF, DME, 20° C.) using [4-(methylthio)phenyl]boronic acid and methyl 4-amino-3-iodo-benzoate as starting material. Flash chromatography (Hexane:EtOAc, 70:30) afforded the title compound as a white solid.

WORKUP

后处理

  1. customPrepared