Ammonium Chloride → HCID 69052507, compound

HRID 1455706Notes

Reaction equation

HRID 1455706 reaction equation
[C:1]([C:7]1[CH:8]=[C:9]2[C:13](=[CH:14][C:15]=1[N+:16]([O-])=O)[C:12](=[O:19])[CH2:11][CH2:10]2)#[C:2][CH2:3][CH2:4][CH2:5][CH3:6].[NH4+].[Cl-]>C(O)C.O.[Fe]>[NH2:16][C:15]1[CH:14]=[C:13]2[C:9]([CH2:10][CH2:11][C:12]2=[O:19])=[CH:8][C:7]=1[C:1]#[C:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

6

Reactant 2

HCID 25517Ammonium ChlorideHCID 69048237HCID 69048237, compound

Product 1

HCID 69052507HCID 69052507, compound

Reagents, catalysts & solvents 3

HCID 23925IronCatalystHCID 702EthanolSolventHCID 962WaterSolvent

Procedure

A mixture of 5-hex-1-ynyl-6-nitroindan-1-one (8.2 g, 31.8 mmol), NH4Cl (0.84 g) and Fe (8.88 g, 0.159 mol) in ethanol (97 ml) and water (32 ml) is heated at reflux for 45 minutes.

Workup

  1. temperatureis heated
  2. temperatureat reflux for 45 minutes

Sources & evidence

ORD record
ord-86f83d5b51e74e3f8f0563bb43ded1b8
Source dataset
uspto-grants-2009_01
Patent number
US07482484B2

Reaction notes

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