Triphenylphosphine → HCID 86753397, compound

HRID 1456606Notes

Reaction equation

HRID 1456606 reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6]Cl)=[C:4]([O:10][CH2:11][O:12][CH3:13])[CH:3]=1.[C:14]1([P:20]([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C1(C)C=CC=CC=1>[Cl-:1].[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][P+:20]([C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)=[C:4]([O:10][CH2:11][O:12][CH3:13])[CH:3]=1

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 22106943HCID 22106943, compound

Product 1

HCID 86753397HCID 86753397, compoundYield 162.9%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

3.38 g of 4-chloro-2-methoxymethoxybenzyl chloride [prepared as described in step (c) above] were dissolved in 50 ml of toluene, and then 6.02 g of triphenylphosphine were added to the resulting solution. The resulting mixture was heated under reflux for 15.5 hours. At the end of this time, the reaction mixture was cooled on ice, and the crystals which precipitated were collected by filtration, and dried in vacuo, to give 6.02 g (yield 82%) of the title compound.

Workup

  1. temperatureThe resulting mixture was heated
  2. temperatureunder reflux for 15.5 hours
  3. temperatureAt the end of this time, the reaction mixture was cooled on ice
  4. customthe crystals which precipitated
  5. filtrationwere collected by filtration
  6. customdried in vacuo

Sources & evidence

ORD record
ord-1490a6e5e7a54496a8962fa525a0c3fb
Source dataset
uspto-grants-1998_12
Patent number
US05843983

Reaction notes

Loading…