HCID 86195276, compound → HCID 21997027, compound

HRID 1457345Notes

Reaction equation

HRID 1457345 reaction equation
[CH2:1]([S:5]([CH2:8][CH:9]([CH2:15][S:16]([CH2:19][CH2:20][CH2:21][CH3:22])(=[O:18])=[O:17])[C:10]([O:12]CC)=[O:11])(=[O:7])=[O:6])[CH2:2][CH2:3][CH3:4]>Cl>[CH2:1]([S:5]([CH2:8][CH:9]([CH2:15][S:16]([CH2:19][CH2:20][CH2:21][CH3:22])(=[O:18])=[O:17])[C:10]([OH:12])=[O:11])(=[O:6])=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 1

HCID 86195276HCID 86195276, compound

Product 1

HCID 21997027HCID 21997027, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A mixture of 2-[(n-butylsulfonyl)methyl]-3-(n-butylsulfonyl)-propanoic acid, ethyl ester (1.0 g, 3.0 mmol) in 6N hydrochloric acid (20 mL) is refluxed overnight. The mixture is transferred to distilled water and extracted with ethyl acetate. The combined organic extracts are concentrated in vacuo to yield the title compound as a clear, colorless oil.

Workup

  1. temperatureis refluxed overnight
  2. distillationto distilled water
  3. extractionextracted with ethyl acetate
  4. concentrationThe combined organic extracts are concentrated in vacuo

Sources & evidence

ORD record
ord-4c799b1092114cd192fb2d239ccb9b83
Source dataset
uspto-grants-1998_12
Patent number
US05847153

Reaction notes

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